I've been playing SC4 Deluxe since it came out. The isometric view doesn't bother me because that was the state of practice at the time of its release.
With the advent of Windows 10, it will only run as the digital download because the Safe Disk support has been discontinued all the way back to Vista. I run this version on Ubuntu 15.04 with wine-1.7.50. It is, however, a Windows executable and better in native mode.
If you are seriously wanting to get involved in the SC4 community, I suggest you join the forums at www.simtropolis.com
and you might want to go from there to SC4Devotion. Simtropolis has a feature called the Omnibus which is full of tutorials and articles about the game and is probably the best source for information extant.
The best source for the game is GOG, GamersGate or Amazon. It is also sold as a DRM item by Steam and Origin which piss in the standard structure making it a little odd to use after market programs. Origin, for example, denies that the Maxis Studio Released Building Architect Tool (BAT) exists. But Origin is a subsidiary of EA which owns the Maxis Studio, or what's left of it.
The digital download is SimCity 4 Deluxe with the Safe Disk code removed and the two necessary patches published by Maxis Studio included. The only addition that I recommend for new players is the Network Addon Mod (NAM) which has an installer that can be run as often as you like to add or remove features. For openers, I suggest that a new player should only use the network controller, and leave the other features for some other time to explore. The default will give you so much stuff you could well drown in it. The NAM comes with lots of documentation in a separate folder in ~/SimCity 4/NAM Auxiliary Files/Documentation.
SC4 comes with a set of default regions containing many city tiles, some of them laid out as examples/problems. They were created for the original version of the game, so the first problem is to update them to the changes made for Rush Hour. A new player might not want to get involved in that. However, there is a tutorial region called Timbuktu which contains several tutorials that will give you the picture of the game's basic algorithms. Play only the tutorials in this region, and play serious cities in one of the others or download a region (can be tricky) or make your own.
In Simtropolis there is the Simtropolis Exchange (STEX) which contains thousands of pieces of custom content (including a link to the NAM v32, the last stable release). The other things a new player should get from the STEX is any item that has the word 'fix' in the title as these are actual bug fixes. One other item is called 'crime doesnt pay' [sic] and is the fix for police scope which is too small.
On Simtropolis you will also find forums for any city building game up to and including C:S. So have a good look around. You can be a guest, but to access the STEX material you have to be a member. Membership is free. You can also purchase DVDs from the site containing selected custom content. This helps support the site, which is totally volunteer and runs on member donations plus some advertising.